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Hyaluronidase Basic information |
Product Name: | Hyaluronidase | Synonyms: | Hyaluronidase - CAS 37326-33-3 - Calbiochem;HYALURONATE GLYCANOHYDROLASE;HYALURONIDASE BOVINE TESTES;HYALURONIDASE OVINE TESTES;HYALURONIDASE, SALT-FREE, BOVINE;HYALURONIDASE, STREPTOMYCES HYALURONLYTICUS NOV SPECIES;HYALURONIDASE TYPE II;HYALURONIDASE TYPE III | CAS: | 37326-33-3 | MF: | NULL | MW: | 0 | EINECS: | 253-464-3 | Product Categories: | Mol File: | Mol File |
Hyaluronidase Chemical Properties |
storage temp. | -20°C | solubility | Soluble in water, practically insoluble in acetone and in anhydrous ethanol | form | powder | color | yellow-brown |
Safety Statements | 22-24/25 | WGK Germany | 3 | F | 3-10 | HS Code | 35079090 |
Hyaluronidase Usage And Synthesis |
Chemical Properties | White or yellowish-white, amorphous powder. | Uses | Used to promote absorption of fluid into tissues. | Uses | Hyaluronidase from sheep testes has been used:- in flow cytometry
- in the isolation of putative spermatogonial stem cells (SSCs)
- to study the effects of magnetic stimulation in magnetic hydrogel properties
- in immunohistochemistry to visualize collagen type II distribution
- to expose group-III auditory neurons of Muller′s organ for patch-clamp recordings
- for the degeneration of hydrogels
| Definition | Any of a class of soluble enzymes produced in mammalian testes that catalyze cleavage of glycosidic
bonds of oartucular mucopolysaccharides. As a
component of venoms, it reduces the viscosity of
connective tissues and promotes tissue penetration
of the ve | General Description | Hyaluronidase is a hyaluronic acid-metabolizing enzyme. It is found in the venoms of snake, honeybee and hymenoptera. Hyaluronidase degrades hyaluronic acid (HA), which enhances membrane permeability, lowers viscosity and increases tissue permeability. It enhances the diffusion of local anesthetics, lowers the size of myocardial infarction, improves the effects of anticancer drugs and prevents perineal trauma during spontaneous delivery. | Biochem/physiol Actions | Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression. | Purification Methods | Hyaluronidase is purified by chromatography on DEAE-cellulose prior to use. [Distler & Jourdain J Biol Chem 248 6772 1973.] |
Hyaluronidase Preparation Products And Raw materials |
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