4-Nitrosalicylic acid
4-Nitrosalicylic acid
  • CAS No.:619-19-2
Other grades of this product :
4-Nitrosalicylic acid Basic information
Product Name:4-Nitrosalicylic acid
Synonyms:2-HYDROXY-4-NITROBENZOIC ACID;4-NITROSALICYLIC ACID;P-NITRO SALICYLIC ACID;2-hydroxy-4-nitro-benzoicaci;4-nitro-salicylicaci;4-nitro-salicylsaure;2-Hydroxy-nitrobenzoic acid;JRH-04202, 2-Hydroxy-4-nitrobenzoic acid, 97%
CAS:619-19-2
MF:C7H5NO5
MW:183.12
EINECS:210-584-0
Product Categories:Carboxylic Acids;C7;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carbonyl Compounds
Mol File:619-19-2.mol
4-Nitrosalicylic acid Chemical Properties
Melting point 235-239 °C (lit.)
Boiling point 316.77°C (rough estimate)
density 1.6074 (rough estimate)
refractive index 1.6280 (estimate)
storage temp. Sealed in dry,Room Temperature
form Solid or Crystalline Powder
pka2.11±0.13(Predicted)
color White to pale brown
InChIKeyUKWUOTZGXIZAJC-UHFFFAOYSA-N
CAS DataBase Reference619-19-2(CAS DataBase Reference)
EPA Substance Registry SystemBenzoic acid, 2-hydroxy-4-nitro- (619-19-2)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS VO5300100
HS Code 29182900
ToxicityLD50 orl-mus: 650 mg/kg ZNTFA2 6B,183,51
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Nitrosalicylic acid Usage And Synthesis
Chemical PropertiesWhite to yellow crystalline powder
Uses4-Nitrosalicylic Acid is a metabolite in the degradation pathway of 2-chloro-4-nitrobenzoic acid by acinetobacter strain RKJ12.
UsesThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General Description2-Hydroxy-4-nitrobenzoic acid is metabolized to 2,4-dihydroxybenzoic acid (2,4-DHBA) by a mono-oxygenase with the concomitant release of chloride and nitrite ions.
Safety ProfilePoison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.
4-Nitrosalicylic acid Preparation Products And Raw materials
Preparation Products4-Aminosalicylic acid-->Phenyl-4-aminosalicylate-->4-Acetamidosalicylic acid-->2-METHOXY-4-NITROBENZALDEHYDE-->METHYL 4-ACETAMIDO-2-HYDROXYBENZOATE

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