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| 7-Nitroindole Basic information |
| 7-Nitroindole Chemical Properties |
| Melting point | 94-98 °C (lit.) | | Boiling point | 288.82°C (rough estimate) | | density | 1.3264 (rough estimate) | | refractive index | 1.5770 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 13.96±0.30(Predicted) | | color | Light yellow to Yellow to Orange | | Water Solubility | slightly soluble | | BRN | 130874 | | CAS DataBase Reference | 6960-42-5(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 68 | | Safety Statements | 36/37-45 | | WGK Germany | 3 | | RTECS | NM1169000 | | Hazard Note | Irritant | | HazardClass | IRRITANT-HARMFUL | | HS Code | 29339900 |
| 7-Nitroindole Usage And Synthesis |
| Chemical Properties | yellow crystalline powder | | Uses | 7-Nitroindole is a reagent used in chemical synthesis. It has been used in the synthesis of protein kinase and inosine monophosphate inhibitors, beta3 agonists and CCK-1 receptor modulators. 7-Nitroindole has also been used as a photochemical precursor of the 2'-deoxyribonolactone analog. | | Uses | 7-Nitroindole is a useful reactant for the preparation of various compounds and inhibitors. | | Uses | Reactant for preparation of:- Protein kinase inhibitors
- Potential fructose 1,6-bisphosphatase inhibitors
- Factor Xa inhibitors
- Antagonist of the mineralocorticoid receptor
- Antitumor sulfonamides
- Inosine monophosphate dehydrogenase (IMPDH) inhibitors
- Subtype-selective cyclooxygenase (COX) inhibitors
- Thrombin protease-activated receptor (PAR-1) ligands
| | Application | Reactant for preparation of:Protein kinase inhibitorsPotential fructose 1,6-bisphosphatase inhibitorsFactor Xa inhibitorsAntagonist of the mineralocorticoid receptorAntitumor sulfonamidesInosine monophosphate dehydrogenase (IMPDH) inhibitorsSubtype-selective cyclooxygenase (COX) inhibitorsThrombin protease-activated receptor (PAR-1) ligands | | Synthesis Reference(s) | Canadian Journal of Chemistry, 42, p. 1235, 1964 DOI: 10.1139/v64-189 |
| 7-Nitroindole Preparation Products And Raw materials |
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