| 4-Bromo-2-fluoro-N-methylbenzamide Basic information |
| Product Name: | 4-Bromo-2-fluoro-N-methylbenzamide |
| Synonyms: | N-Methyl 4-bromo-2-fluorobenzamide;4-Bromo-2-fluoro-N-methylbenzamide;BenzaMide, 4-broMo-2-fluoro-N-Methyl-;Enzalutamide EP Impurity B;Enzalutamide Impurity 14;N-METHYL 4-BROMO-2-FLUORO;4-Bromo-2-fluoro-N-methylbenzamide;4-Bromo-2-fluoro-N-methylbenzamide(For export only) |
| CAS: | 749927-69-3 |
| MF: | C8H7BrFNO |
| MW: | 232.05 |
| EINECS: | 808-257-8 |
| Product Categories: | blocks;Bromides;Carboxes;FluoroCompounds |
| Mol File: | 749927-69-3.mol |
| 4-Bromo-2-fluoro-N-methylbenzamide Chemical Properties |
| Melting point | 125.0 to 129.0 °C |
| Boiling point | 284.8±30.0 °C(Predicted) |
| density | 1.545±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.76±0.46(Predicted) |
| color | White to Off-White |
| InChIKey | BAJCFNRLEJHPTQ-UHFFFAOYSA-N |
| CAS DataBase Reference | 749927-69-3 |
| Safety Information |
| HS Code | 2924297099 |
| MSDS Information |
| 4-Bromo-2-fluoro-N-methylbenzamide Usage And Synthesis |
| Uses | 4-Bromo-2-fluoro-N-methylbenzamide is an intermediate in the synthesis of MDV 3100 (M199800), is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. |
| 4-Bromo-2-fluoro-N-methylbenzamide Preparation Products And Raw materials |
| Raw materials | 4-Bromo-2-fluorobenzoic acid-->4-BROMO-2-FLUOROBENZOYL CHLORIDE-->Methylamine hydrochloride-->Methylamine |
| Preparation Products | 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE |
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