Ethyl nipecotate
Ethyl nipecotate
  • CAS No.:5006-62-2
Other grades of this product :
Ethyl nipecotate Basic information
Product Name:Ethyl nipecotate
Synonyms:RARECHEM AH CK 0179;PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER;NIPECOTIC ACID ETHYL ESTER;NIPECOTINIC ACID ETHYL ESTER;ethylenipecotate;3-PIPERIDINECARBOXYLIC ACID ETHYL ESTER;Ethyl nipecotate SynonyMs: Ethyl 3-piperidinecarboxylate;NSC 158451
CAS:5006-62-2
MF:C8H15NO2
MW:157.21
EINECS:225-681-3
Product Categories:Nitrogen cyclic compounds;Miscellaneous;Piperidine;API intermediates;Piperazine
Mol File:5006-62-2.mol
Ethyl nipecotate Chemical Properties
Melting point 165-167 °C
Boiling point 102-104 °C/7 mmHg (lit.)
density 1.012 g/mL at 25 °C (lit.)
vapor pressure 7.78Pa at 25℃
refractive index n20/D 1.460(lit.)
Fp 195 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka9.35±0.10(Predicted)
form Liquid
color Clear colorless to yellow-brown
Specific Gravity1.011.012
Water Solubility miscible
Sensitive Air Sensitive
BRN 118388
LogP1.15
CAS DataBase Reference5006-62-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,C
Risk Statements 36/37/38-34-20/21/22
Safety Statements 26-36/37/39-45-36-24/25-23
RIDADR UN2735
WGK Germany 3
Hazard Note Irritant
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Ethyl nipecotate Usage And Synthesis
Chemical Propertiesclear colorless to yellow-brown liquid
UsesEthyl Nipecotate is used in the synthesis of cyanothiophene inhibitors of peptidoglycan biosynthesis.
UsesEthyl nipecotate was used in the synthesis of:
  • α,α′-bis[3-(N,N-diethylcarbamoyl)-piperidino]-p-xylene
  • 2-amino-4-thiazolyl derivative of 3-(iso-propyl-3-piperidinyl)phenol
Ethyl nipecotate Preparation Products And Raw materials
Preparation Products(S)-1-Boc-3-(hyroxymethyl)piperidine-->(R)-1-Boc-3-(hyroxymethyl)piperidine

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