ALPHA-HELICAL CRF (9-41)
ALPHA-HELICAL CRF (9-41)
  • CAS No.:99658-03-4
Other grades of this product :
ALPHA-HELICAL CRF (9-41) Basic information
Product Name:ALPHA-HELICAL CRF (9-41)
Synonyms:CORTICOTROPIN RELEASING FACTOR ANTAGONIST;H-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-GLU-ALA-GLU-GLN-ALA-ALA-LEU-ASN-ARG-LEU-LEU-LEU-GLU-GLU-ALA-NH2;ASP-LEU-THR-PHE-HIS-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-ALA-GLU-GLN-ALA-LEU-ASN-ARG-LEU-LEU-GLU-ALA-NH2;ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-MET-LEU-GLU-MET-ALA-LYS-ALA-GLU-GLN-GLU-ALA-GLU-GLN-ALA-ALA-LEU-ASN-ARG-LEU-LEU-LEU-GLU-GLU-ALA-NH2;ALPHA-HELICAL CORTICOTROPIN RELEASING FA CTOR;α-helical corticotropin releasing factor fragment (9-41);ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR (9-41);ALPHA-HELICAL CORTICOTROPIN RELEASING FACTOR FRAGMENT (9-41)
CAS:99658-03-4
MF:C22H25IN2O6
MW:540.34817
EINECS:
Product Categories:CRF receptor and related
Mol File:99658-03-4.mol
ALPHA-HELICAL CRF (9-41) Chemical Properties
storage temp. −20°C
form powder
color white
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
ALPHA-HELICAL CRF (9-41) Usage And Synthesis
Biochem/physiol ActionsThe corticotropin releasing factor (CRF) antagonist α-helical CRF [9-41] exhibits 10-fold higher affinity for rat CRF2α receptors over human CRF2α receptors. It has been used to elucidate the role of CRF in various physiological systems. In colonic epithelium, it abolishes CRF-induced changes in ion secretion, and significantly inhibits CRF-stimulated conductance. It antagonizes the CRF-induced proinflammatory degranulation of perivascular mast cells that are activated in response to acute psychological stress and CRF secretion.
ALPHA-HELICAL CRF (9-41) Preparation Products And Raw materials

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