15-hexadecynoic acid
15-hexadecynoic acid
  • CAS No.:99208-90-9
Other grades of this product :
15-hexadecynoic acid Basic information
Product Name:15-hexadecynoic acid
Synonyms:15-hexadecynoic acid;Palmitic Acid Alkyne;hexadec-15-ynoic acid;15-HEXADECYNOIC ACID;PALMITIC ACID (15-YNE);Palmitic acid (15-yne);Alkynyl Palmitic Acid;Boc-β-homoarginine;15-hexadecyn-1-oic acid
CAS:99208-90-9
MF:C16H28O2
MW:252.39
EINECS:
Product Categories:
Mol File:99208-90-9.mol
15-hexadecynoic acid Chemical Properties
Melting point 59.1°C (estimate)
Boiling point 409.64°C (rough estimate)
density 0.9310 (rough estimate)
refractive index 1.4217 (estimate)
storage temp. -20°C
Safety Information
MSDS Information
15-hexadecynoic acid Usage And Synthesis
DescriptionAlkynyl palmitic acid can be used to identify and characterize the post-translational S-palmitoylation of proteins with Click Chemistry.
Uses15-hexadecynoic acid is a form of palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in linking reactions, known as click chemistry; this chemistry is characterized by high dependability and specificity of the azide-alkyne bioconjugation reactions. The use of palmitic acid alkyne and related lipids in isolating palmitoylated proteins has been described.
UsesPalmitic acid (15-yne) has been used as a component of fatty acid probe stock solution for the optimization of Alk-C16 incorporation onto cellular proteins. It is also suitable for metabolic labeling.
Biochem/physiol ActionsAlkynyl palmitic acid (aPA) is a modified palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′. The click chemistry reactions are rapid, convenient, versatile and regiospecific. They are easy to purify. aPA can be used for isolating palmitoylated proteins.
15-hexadecynoic acid Preparation Products And Raw materials

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