Other grades of this product :
| FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Basic information |
| FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Chemical Properties |
| storage temp. | Desiccate at RT | | solubility | H2O: soluble >10mg/mL | | form | powder | | color | off-white | | optical activity | [α]27/D 7.2°, c = 0.3 in methanol(lit.) |
| WGK Germany | 3 | | RTECS | CV2450000 |
| FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Usage And Synthesis |
| Uses | Dopamine receptor antagonist | | Uses | S-(?)-Eticlopride hydrochloride has been used in astrocyte-neuron coculture and functional magnetic resonance imaging (fMRI) experiments. | | Biological Activity | Selective dopamine D 2 /D 3 receptor antagonist (K i values are 0.50 and 0.16 nM respectively). Antipsychotic. | | Biochem/physiol Actions | Potent and selective D2 dopamine receptor antagonist. Eticlopride is highly specific for DAD2?receptors than pimozide or haloperidol. The gene encoding the D2 dopamine receptor (DRD2) is linked with a several disorders including Parkinson′s disease, schizophrenia, and susceptibility to alcoholism. |
| FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Preparation Products And Raw materials |
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![FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride](/img/97612-24-3.jpg "FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride")
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