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| Methyltrienolone Basic information |
| Methyltrienolone Chemical Properties |
| Melting point | 170° | | alpha | D20 -58.7° (c = 0.5 in ethanol) | | Boiling point | 485.9±45.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: ≥10mg/mL | | form | powder | | pka | 14.79±0.40(Predicted) | | color | light yellow to yellow | | optical activity | [α]/D -48 to -68° | | InChIKey | CCCIJQPRIXGQOE-XWSJACJDSA-N | | CAS DataBase Reference | 965-93-5(CAS DataBase Reference) |
| Methyltrienolone Usage And Synthesis |
| Description | Methyltrienolone is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug and a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and in prostatic tumors.
| | Chemical Properties | Pale Yellow Solid | | Uses | An anabolic steroid. | | Definition | ChEBI: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. | | Biochem/physiol Actions | Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. R1881, also known as methyltrienolone, is a synthetic androgen. It is the gold standard AR agonist. | | References | https://en.wikipedia.org/wiki/Metribolone
https://www.drugbank.ca/drugs/DB02998
https://pubchem.ncbi.nlm.nih.gov/compound/Methyltrienolone
Kazlauskas R. (2010) Designer Steroids. In: Thieme D., Hemmersbach P. (eds) Doping in Sports: Biochemical Principles, Effects and Analysis. Handbook of Experimental Pharmacology, vol 195. Springer, Berlin, Heidelberg
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| Methyltrienolone Preparation Products And Raw materials |
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