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PHENCYCLIDINE HYDROCHLORIDE Basic information | Description |
PHENCYCLIDINE HYDROCHLORIDE Chemical Properties |
Hazard Codes | T | Risk Statements | 25 | Safety Statements | 36/37-45 | RIDADR | UN 2811 6.1/PG 3 | WGK Germany | 3 | RTECS | TN2272600 | HazardClass | 6.1(a) | PackingGroup | I | HS Code | 2933330000 | Toxicity | LD50 orally in mice: 76.5 mg/kg (Bailey) |
PHENCYCLIDINE HYDROCHLORIDE Usage And Synthesis |
Description | Phencyclidine hydrochloride (PCP) is a psychoactive drug that has inhibitory, excitatory, analgesic and hallucinogenic effects on the central nervous system. Its chemical name is 1-(1-phenylcyclohexane)piperidine. It is a dissociative drug once used by anesthesiologists as an anesthetic with hallucinogenic and neurotoxic effects. | Chemical Properties | Crystalline Solid | Uses | Anesthetic (intravenous).
Controlled substance (depressant). | Uses | Controlled substance (depressant). Anesthetic (intravenous). | Brand name | Sernylan (Parke-Davis). | Biological Activity | Non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats. | Biochem/physiol Actions | σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel. | Safety Profile | Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by ingestion and intravenousroutes: distorted perceptions, euphoria, excitement,hallucinations, and paresthesia. An experimental teratogen.Other experime |
PHENCYCLIDINE HYDROCHLORIDE Preparation Products And Raw materials |
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