Other grades of this product :
| 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Basic information |
| Product Name: | 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide | | Synonyms: | 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide;PF 429242;o)Meth (2-MetR)-4-((diethylaMinyl)-Nhoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide;4-((diethylaMino)Methyl)-N-(2-Methoxyphenethyl)-N-(pyrrolidin-3-yl)benzaMide;PF-429242 dihydrochloride;4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide dihydrochloride;Benzamide, 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-;-4-((Diethylamino) | | CAS: | 947303-87-9 | | MF: | C25H35N3O2 | | MW: | 409.56 | | EINECS: | | Product Categories: | | Mol File: | 947303-87-9.mol |
| 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Chemical Properties |
| Boiling point | 562.2±50.0 °C(Predicted) | | density | 1.11±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | H2O: soluble15mg/mL, clear | | form | powder | | pka | 9.47±0.10(Predicted) | | color | white to beige | | InChIKey | XKPJTOHUPQWSOJ-HSZRJFAPSA-N |
| Hazard Codes | Xi,N | | Risk Statements | 36/37/38-50 | | Safety Statements | 26-61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 |
| 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Usage And Synthesis |
| Uses | PF 429242 is a novel subtilisin kexin isozyme-1/site-1 (SKI-1/S1P) protease inhibitor. PF 429242 is a sterol regulatory element-binding protein1 (SREBP1) inhibitor and has been shown to decrease pancreatic cancer cell viability and proliferation. | | Biochem/physiol Actions | PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV. |
| 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide Preparation Products And Raw materials |
|
![4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide](/img/947303-87-9.jpg "4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide")
日本语
한국어
Français
Deutsch
España
Türkiye