1-HYDROXY-1-CYCLOHEXANECARBONITRILE
1-HYDROXY-1-CYCLOHEXANECARBONITRILE
  • CAS No.:931-97-5
Other grades of this product :
1-HYDROXY-1-CYCLOHEXANECARBONITRILE Basic information
Product Name:1-HYDROXY-1-CYCLOHEXANECARBONITRILE
Synonyms:CYCLOHEXANONE CYANOHYDRIN;1-HYDROXY-1-CYCLOHEXANECARBONITRILE;1-HYDROXY-CYCLOHEXANECARBONITRILE;1-Hydroxy-cyclohexancarbonitril;1-hydroxy-cyclohexanecarbonitril;CYCLOHEXANECARBONITRILE,1-HYDROXY-;1-Cyano-1-hydroxycyclohexane;1-Hydroxy-1-cyanocyclohexane
CAS:931-97-5
MF:C7H11NO
MW:125.17
EINECS:213-246-0
Product Categories:Miscellaneous;Cycloalkanes
Mol File:931-97-5.mol
1-HYDROXY-1-CYCLOHEXANECARBONITRILE Chemical Properties
Melting point 32-35 °C (lit.)
Boiling point 132 °C/19 mmHg (lit.)
density 1.031
refractive index 1.4693
Fp >230 °F
storage temp. 2-8°C
pka11.45±0.20(Predicted)
CAS DataBase Reference931-97-5(CAS DataBase Reference)
EPA Substance Registry SystemCyclohexanone cyanohydrin (931-97-5)
Safety Information
Hazard Codes T+
Risk Statements 28
Safety Statements 45
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS GU7710000
TSCA Yes
HazardClass 6.1
PackingGroup II
MSDS Information
ProviderLanguage
SigmaAldrich English
1-HYDROXY-1-CYCLOHEXANECARBONITRILE Usage And Synthesis
UsesCyclohexanone cyanohydrin was employed as substrate during high-throughput screening assay for hydroxynitrile lyase activity. It was used in preparation of 1-aminomethyl cyclohexanol via catalytic hydrogenation reaction.
Synthesis Reference(s)Tetrahedron Letters, 19, p. 3773, 1978 DOI: 10.1016/S0040-4039(01)95055-5
General DescriptionBrown solid.
Air & Water ReactionsWater soluble. Reacts slowly with water .
Reactivity Profile1-HYDROXY-1-CYCLOHEXANECARBONITRILE is an a-hydroxonitrile. Incompatible with acids; mixing nitriles with strong oxidizing acids can lead to violent reactions. Incompatible with oxidizing agents such as peroxides and epoxides. Mixing with bases can produce poisonous and flammable hydrogen cyanide. May be hydrolyzed exothermically in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). May react vigorously with reducing agents.
Fire HazardFlash point data regarding 1-HYDROXY-1-CYCLOHEXANECARBONITRILE are not available, however, 1-HYDROXY-1-CYCLOHEXANECARBONITRILE is probably combustible.
1-HYDROXY-1-CYCLOHEXANECARBONITRILE Preparation Products And Raw materials
Preparation Products1-hydroxycyclohexane-1-carboxamide-->ETHYL 1-HYDROXYCYCLOHEXANE-CARBOXYLATE-->1-(aminomethyl)cyclohexan-1-ol

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