Other grades of this product :
| Methyl-piperidino-pyrazole hydrate Basic information |
| Product Name: | Methyl-piperidino-pyrazole hydrate | | Synonyms: | 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride hydrate;MPP dihydrochloride hydrate;Methyl-piperidino-pyrazole hydrate;Methyl-piperidino-pyrazole dihydrochloride hydrate;MPP dihydrochloride (289726-02-9 Free base) | | CAS: | 911295-24-4 | | MF: | C29H32ClN3O3 | | MW: | 506.04 | | EINECS: | | Product Categories: | | Mol File: | 911295-24-4.mol |
| Methyl-piperidino-pyrazole hydrate Chemical Properties |
| solubility | DMSO: soluble ≥20mg/mL | | form | white powder |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| Methyl-piperidino-pyrazole hydrate Usage And Synthesis |
| Uses | MPP Dihydrochloride is a pharmacological estrogen receptor antagonist. It cannot block EE2 induced luciferase activity with any isoform of zebrafish estrogen receptor. | | Uses | MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:- in human breast cancer MCF-7 cells
- to pre-treat endometrial ex vivo organ cultures (EVOCs)
- to treat pituitary glands to monitor luteinizing hormone secretion
| | General Description | Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol. | | Biochem/physiol Actions | MPP dihydrochloride is a specific estrogen receptor α antagonist. |
| Methyl-piperidino-pyrazole hydrate Preparation Products And Raw materials |
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