3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
  • CAS No.:80288-49-9
Other grades of this product :
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Basic information
Product Name:3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
Synonyms:FURAFYLLINE;3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE;Furafylline,3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione;FURAFYLLINE INHIBITOR OF CYTOCHRO;1H-Purine-2,6-dione, 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-;3-(Furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione
CAS:80288-49-9
MF:C12H12N4O3
MW:260.25
EINECS:200-158-5
Product Categories:
Mol File:80288-49-9.mol
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Chemical Properties
Melting point >162°C (dec.)
Boiling point 543.6±60.0 °C(Predicted)
density 1.443±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility ethanol: 0.33 mg/mL
form solid
pka8.62±0.70(Predicted)
color white
InChIKeyKGQZGCIVHYLPBH-UHFFFAOYSA-N
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Usage And Synthesis
Usesinhibitor
UsesFurafylline is a selective inhibitor of human cytochrome P450. It is also reported to inhibit the oxidation of caffeine.
Biochem/physiol ActionsFurafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Preparation Products And Raw materials

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