![6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride](/img/789488-77-3.jpg "6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride")
| 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Basic information |
| Product Name: | 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride |
| Synonyms: | 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride;ENMD-1068 hydrochloride;ENMD-1068;ENMD-1068 (ENMD1068);6-amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one;ENMD-1068 HCl |
| CAS: | 789488-77-3 |
| MF: | C15H29N3O2 |
| MW: | 283.41 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 789488-77-3.mol |
| 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Chemical Properties |
| storage temp. | 2-8°C |
| solubility | H2O: soluble25mg/mL, clear |
| form | powder |
| color | white to beige |
| MSDS Information |
| 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Usage And Synthesis |
| Uses | ENMD-1068 hydrochloride has been used as a protease-activated receptor 2 (PAR2) antagonist to determine the pathway responsible for paw edema induced by Crotalus durissus terrificus venom serine protease (Cdtsp 2). |
| Biochem/physiol Actions | ENMD-1068 is an antagonist of protease-activated receptor 2 (PAR2). The compound blocks TNFα production in synovial explants from patients with arthritis, and inhibits mast cell tryptase-induced recruitment of eosinophils into the pleural cavity of mice. |
| 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride Preparation Products And Raw materials |
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