(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
  • CAS No.:78508-96-0
Other grades of this product :
(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE Basic information
Product Name:(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE
Synonyms:(S)-(-)-5-HYDROXYMETHYL-2(5H)-FURANONE;(S)-(+)-5-HYDROXYMETHYL-2(5H)-FURANONE;(S)-(+)-HYDROXYMETHYL-2(5H)-FURANONE;(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE;(S)-HYDROXYMETHYL-3(2H)-FURANONE;5-(Hydroxymethyl)-2(5H)-furanone;(S)-(-)-5-(Hydroxymethyl)-2(5H)-furanone, 99% ,ee:99%;(S)-(-)-5-(Hydroxymethyl)-2(5H)-furanone99% (99% ee)
CAS:78508-96-0
MF:C5H6O3
MW:114.1
EINECS:
Product Categories:Chiral Reagent;Chiral Building Blocks;Furans;Heterocyclic Building Blocks
Mol File:78508-96-0.mol
(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE Chemical Properties
Melting point 41-43 °C(lit.)
Boiling point 173.58°C (rough estimate)
density 1.2583 (rough estimate)
refractive index 1.4630 (estimate)
Fp >230 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly), Water (Sparingly)
form Solid
pka13.51±0.10(Predicted)
color Off-White Low-Melting
optical activity[α]20/D 144°, c = 1 in H2O
Water Solubility Slightly soluble in water.
Sensitive Hygroscopic
BRN 3537455
Stability:Moisture Sensitive
CAS DataBase Reference78508-96-0(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
3-10
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
Uses(S)-(-)-5-Hydroxymethyl-2(5H)-furanone is used in the preparation of partially saturated heterocycles via a diastereoselective ring chain formation. It is also used in the synthesis of (1R,3S)-cis-chrysanthemic acid.
Uses(S)-(?)-5-Hydroxymethyl-2(5H)-furanone can be used as a starting material in the preparation of:
  • Partially saturated heterocycles via a diastereoselective ring chain formation.
  • A natural product named (+)-muscarine.
  • 3′-Ethynylthymidine as a possible antiviral agent.
(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE Preparation Products And Raw materials
Preparation Products5-methylenefuran-2(5H)-one-->(S)-5-Hydroxymethyldihydrofuran-2-one

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