P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
  • CAS No.:75522-97-3
Other grades of this product :
P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Basic information
Product Name:P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT
Synonyms:adenosine5’-(hexahydrogenpentaphosphate),5’.fwdarw.5’-esterwithadenosine,;AP5A;AP5A, 3LI;AP5A, LI3;A(5′)P5(5′)A trilithium salt;P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT;P1,P5-DI(ADENOSINE-5'-PENTAPHOSPHATE), TRILITHIUM;Adenosine 5'-(hexahydrogen pentaphosphate), 5'->5'-ester with adenosine, trilithium salt
CAS:75522-97-3
MF:C20H26Li3N10O22P5
MW:934.17
EINECS:278-237-6
Product Categories:Organic-metal salt
Mol File:75522-97-3.mol
P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Chemical Properties
storage temp. -20°C
solubility H2O: soluble50mg/mL
form powder
color white to off-white
Safety Information
WGK Germany 3
HS Code 29349990
MSDS Information
P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Usage And Synthesis
Chemical PropertiesWhite powder
UsesP1,P5-Di(adenosine-5′) pentaphosphate trilithium salt has been used as a adenylate kinase inhibitor and as a component of pre-AMPPNP rigor solution for treating muscle fibres.
Biochem/physiol ActionsA diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.
P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Preparation Products And Raw materials

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