Other grades of this product :
| (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Basic information |
| Product Name: | (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE | | Synonyms: | (+/-)-SKF-81297 HYDROBROMIDE;(+/-)-6-CHLORO-PB HYDROBROMIDE;(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE;6-CHLORO-2,3,4,5-TETRAHYDRO-1-PHENYL-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE;SKF 81297 HYDROBROMIDE;sk&f81297;(+-)-6-CHLORO-PB HYDROBROMIDE (+-)-SKF-8 1297, HCL;6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepinehydrobromide | | CAS: | 71636-61-8 | | MF: | C16H17BrClNO2 | | MW: | 370.67 | | EINECS: | | Product Categories: | Dopamine receptor | | Mol File: | 71636-61-8.mol |
| (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties |
| storage temp. | Desiccate at +4°C | | solubility | H2O: 1.7 mg/mL | | form | solid | | color | gray |
| (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Usage And Synthesis |
| Uses | (±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal?regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice. It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats. | | Biological Activity | Dopamine D 1 -like receptor agonist. Centrally active following systemic administration in vivo . | | Biochem/physiol Actions | (+/-)-6-Chloro-PB HBr is a full D1 dopamine receptor agonist. |
| (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials |
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