| 1-(3-Chlorophenyl)piperazine hydrochloride Basic information |
| Product Name: | 1-(3-Chlorophenyl)piperazine hydrochloride |
| Synonyms: | 1-(3-CHLOROPHENYL)PIPERAZINE 2HCL;1-(3-Chlorophenyl)piperazine hydrochloride,97%;N-(3-Chlorophenyl) Piperazine HCl;1-(3-Chlorophenyl)piperazine hydrochloride;1-(3-CHLOROPHENYL)-PIPERAZINE HCL (MCLPPB);Piperazine, 1-(3-chlorophenyl)-, hydrochloride;1-(3-Chlorophenyl)piperidine/hydrochloric acid,(1:x);1-(3-Chlorophenyl)piperazine hydrochloride ,98% |
| CAS: | 65369-76-8 |
| MF: | C10H14Cl2N2 |
| MW: | 233.14 |
| EINECS: | 265-718-0 |
| Product Categories: | Serotonin receptor;Piperazines;API intermediates |
| Mol File: | 65369-76-8.mol |
| 1-(3-Chlorophenyl)piperazine hydrochloride Chemical Properties |
| Melting point | 210-214 °C (dec.)(lit.) |
| density | 1,193g/cm |
| refractive index | 1,598-1,600 |
| Fp | 9℃ |
| storage temp. | Store at RT |
| solubility | methanol: soluble |
| form | Solid |
| color | Pale brown |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 65369-76-8(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi,Xn,T,F |
| Risk Statements | 36/37/38-22-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-36-24/25-45-36/37-16-7 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29339900 |
| MSDS Information |
| Provider | Language |
|---|---|
| 1-(m-Chlorophenyl)piperazine hydrochloride | English |
| SigmaAldrich | English |
| 1-(3-Chlorophenyl)piperazine hydrochloride Usage And Synthesis |
| Chemical Properties | Off-white solid |
| Uses | Chlorophenyl Piperazine Hydrochloride Salt is a useful intermediate for organic synthesis and other chemical properties. Trazodone impurity. |
| General Description | 1-(3-Chlorophenyl)-piperazine, also known as meta-chlorophenylpiperazine or mCPP, is a designer drug analog of aryl-substituted piperazines. A stimulant, serotonin antagonist and reuptake inhibitor (SARU), mCPP can also be detected as a primary urinary metabolite of the antidepressant drug trazadone. This certified solution standard is suitable for use in piperazine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications. |
| Biological Activity | 5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo . |
| 1-(3-Chlorophenyl)piperazine hydrochloride Preparation Products And Raw materials |
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