(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol
  • CAS No.:53732-47-1
Other grades of this product :
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol Basic information
Product Name:(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol
Synonyms:(S)-(+)-ALPHA-TETRALOL;(S)-(+)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL;(S)-(+)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL, 9 9% (99% EE/HPLC);(S)-(+)-1,2,3,4-tetrahydro-1-naphtol;(s)-(+)-α-tetralol;(S)-1,2,3,4-Tetrahydronaphthalen-1-ol;(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol 99%;(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol
CAS:53732-47-1
MF:C10H12O
MW:148.2
EINECS:
Product Categories:Chiral Building Blocks;Simple Alcohols (Chiral);Chiral;Synthetic Organic Chemistry
Mol File:53732-47-1.mol
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol Chemical Properties
Melting point 37-39 °C
Boiling point 92 °C / 1.8mmHg
density 1.09 g/mL at 25 °C(lit.)
refractive index 33 ° (C=2.5, CHCl3)
Fp 113 °C
solubility almost transparency in Methanol
pka14.33±0.20(Predicted)
form powder to crystal
color White to Almost white
optical activity[α]20/D +33±1°, c = 2.5% in chloroform
BRN 2208779
CAS DataBase Reference53732-47-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS QL5075000
MSDS Information
ProviderLanguage
SigmaAldrich English
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol Usage And Synthesis
Uses(S)?-?(+)?-?1,?2,?3,?4-?Tetrahydro-?1-?naphthol is a building block used in pharmaceutical chemistry such as in the synthesis of a potent and orally bioavailable GPR40 agonist acting as a novel insulin secretagogues with low risk of hypoglycemia
General DescriptionChiral building block.
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol Preparation Products And Raw materials
Raw materials(R)-(-)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL-->1,2-DIHYDRONAPHTHALENE-->Vinyl acetate-->1,2,3,4-Tetrahydro-1-naphthol-->1-Tetralone

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