Tetramethylene sulfoxide
Tetramethylene sulfoxide
  • CAS No.:1600-44-8
Other grades of this product :
Tetramethylene sulfoxide Basic information
Product Name:Tetramethylene sulfoxide
Synonyms:TetraMethylene sulfoxide, 98+% 5GR;Tetrahydrothiophene 1-oxide 96%;TETRAMETHYLENE SULFOXIDE;TETRAMETHYLENE SULPHOXIDE;tetrahydro-thiophen1-oxide;Tetrametylene sulfoxide;Thiolane 1-oxide;Thiophane 1-oxide
CAS:1600-44-8
MF:C4H8OS
MW:104.17
EINECS:216-493-2
Product Categories:
Mol File:1600-44-8.mol
Tetramethylene sulfoxide Chemical Properties
Boiling point 235-237 °C(lit.)
density 1.158 g/mL at 25 °C(lit.)
refractive index n20/D 1.52(lit.)
Fp >230 °F
form Liquid
color Clear colorless to yellow
Water Solubility Fully miscible in water.
BRN 105274
CAS DataBase Reference1600-44-8(CAS DataBase Reference)
EPA Substance Registry SystemThiophene, tetrahydro-, 1-oxide (1600-44-8)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS XN0830000
TSCA T
HS Code 29041000
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Tetramethylene sulfoxide Usage And Synthesis
Chemical Propertiesclear colorless to yellow liquid
UsesIn a comparative study of aromatic fluorodenitration with Potassium fluoride, in several dipolar aprotic solvents, a much faster reaction rate was observed with DMSO or tetramethylene sulfoxide than with the more commonly used Sulfolane.
Synthesis Reference(s)Journal of the American Chemical Society, 63, p. 2939, 1941 DOI: 10.1021/ja01856a021The Journal of Organic Chemistry, 50, p. 1787, 1985 DOI: 10.1021/jo00210a055Synthetic Communications, 24, p. 2393, 1994 DOI: 10.1080/00397919408010545
Purification MethodsShake the oxide with BaO for 4 days, then distil it from CaH2 under reduced pressure. [Beilstein 17 III/IV 36, 17/1 V 38.]
Tetramethylene sulfoxide Preparation Products And Raw materials
Preparation ProductsTETRAHYDROTHIOPHENE SULFOXIMINE

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