N,N'-bis(salicylideneamino)ethane-manganese(II) Basic information |
Product Name: | N,N'-bis(salicylideneamino)ethane-manganese(II) |
Synonyms: | N,N'-Bis(salicylidene)-1,2-ethylenediamine-manganese(II) (SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-alphaN)methylidyne]]bis[phenolato-alphaO]](2-)]manganese;(Salen)manganese(III) chloride;(SP-5-13)-Chloro[[2,2′-[1,2-ethanediylbis(nitrilomethylidyne)]bis[phenolato]](2-)-N,N′,O,O′]-manganese;Chloro(bis(salicylidene)ethylenediamine)manganese;Chloro[N,N′-ethylenebis(salicylideneaminato)]manganese;Manganese(salen) chloride;N,N'-bis(salicylideneamino)ethane-manganese(II);EUK-8 |
CAS: | 53177-12-1 |
MF: | C16H14ClMnN2O2 |
MW: | 356.685609 |
EINECS: | |
Product Categories: | |
Mol File: | 53177-12-1.mol |
N,N'-bis(salicylideneamino)ethane-manganese(II) Chemical Properties |
storage temp. | -20°C |
solubility | H2O: soluble1mg/mL, clear |
form | powder |
color | , faint to very dark brown |
Safety Information |
WGK Germany | 3 |
MSDS Information |
N,N'-bis(salicylideneamino)ethane-manganese(II) Usage And Synthesis |
Uses | [N,N 0-Disalicylidene-1,2-ethanediaminato-(2-)]manganese(III) Chloride is an oxidation catalysts and an enzyme mimetic. It also functions as an intermediate in the synthesis of manganese(III) complexes with fluorinated salen derivatives that exhibits antioxidant properties. |
Biochem/physiol Actions | EUK-8 is a salen manganese complex that exhibit potent antioxidant activities. EUK-8 is a superoxide dismutase (SOD) that inhibits amyloid fibril formation, including islet amyloid polypeptide (IAPP), β-amyloid and lysozyme amyloid aggregation. It appears that EUK-8 disrupts the pre-formed amyloid fibrils. EUK-8 increases the viability of the SK-N-MC cells exposed to preformed IAPP fibrils. |
N,N'-bis(salicylideneamino)ethane-manganese(II) Preparation Products And Raw materials |
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