Other grades of this product :
| 7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Basic information |
| 7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Chemical Properties |
| Melting point | >300 °C | | Boiling point | 716.9±62.0 °C(Predicted) | | density | 1.54±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | DMSO: 15 mg/mL at ≥60 °C | | form | solid | | pka | 2.65±0.20(Predicted) |
| 7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Usage And Synthesis |
| Uses | 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid is a calcium/calmodulin-dependent protein kinase inhibitor and was found to upregulate various AhR target genes in human macrophages. | | Biological Activity | Selective, cell-permeable inhibitor of Ca 2+ -calmodulin-dependent protein kinase kinase (K i values are 80 and 15 ng/ml for inhibition of CaM-KK α and CaM-KK β respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. |
| 7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Preparation Products And Raw materials |
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![7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE](/img/52029-86-4.jpg "7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE")
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