2-Thiohydantoin
2-Thiohydantoin
  • CAS No.:503-87-7
Other grades of this product :
2-Thiohydantoin Basic information
Product Name:2-Thiohydantoin
Synonyms:2-Thioguidanthion;2-thio-hydantoi;2-thioxo-4-imidazolidinon;2-Thioxo-4-imidazolidinone;2-Thioxo-4-imidazolinone;4-Imidazolidinone,2-thioxo-;Glycine thiohydantoin;Hydantoin, 2-thio-
CAS:503-87-7
MF:C3H4N2OS
MW:116.14
EINECS:207-977-4
Product Categories:Building Blocks;Chemical Synthesis;Ring Systems;Building Blocks;Heterocyclic Building Blocks;Heterocyclic Building Blocks;Imidazolines/Imidazolidines
Mol File:503-87-7.mol
2-Thiohydantoin Chemical Properties
Melting point 229-231 °C (dec.)(lit.)
density 1.346 (estimate)
vapor density 4 (vs air)
refractive index 1.6550 (estimate)
storage temp. Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Crystalline Powder
pka8.50±0.10(Predicted)
color White
CAS DataBase Reference503-87-7(CAS DataBase Reference)
NIST Chemistry Reference4-Imidazolidinone, 2-thioxo-(503-87-7)
EPA Substance Registry System4-Imidazolidinone, 2-thioxo- (503-87-7)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-22
Safety Statements 36
WGK Germany 3
RTECS MU4200000
TSCA Yes
HS Code 2934999090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
2-Thiohydantoin Usage And Synthesis
Chemical PropertiesBROWN CRYSTALLINE POWDER
UsesReactant for synthesis of:• ;Drugs with antidiabetic activity1• ;Barbituric acid and thiohydantoin derivatives with antimicrobial activity2• ;Possible anticancer agents3• ;Fibroblast growth factor receptor 1 kinase inhibitors4• ;HIV-1 integrase inhibitors5Reactant for persilylation6
Uses2-Thiohydantoin is a useful synthetic intermediate. It is a reactant for synthesis of drugs with antidiabetic activity, barbituric acid and thiohydantoin derivatives with antimicrobial activity, and possible anticancer agents.
UsesReactant for synthesis of:
  • Drugs with antidiabetic activity
  • Barbituric acid and thiohydantoin derivatives with antimicrobial activity
  • Possible anticancer agents
  • Fibroblast growth factor receptor 1 kinase inhibitors
  • HIV-1 integrase inhibitors
Reactant for persilylation
2-Thiohydantoin Preparation Products And Raw materials
Preparation ProductsPARABANIC ACID

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