CYANOMETHYLENETRIBUTYLPHOSPHORANE One Chongqing Chemdad Co. ，Ltd

Product

CYANOMETHYLENETRIBUTYLPHOSPHORANE

CAS No.：157141-27-0

Other grades of this product :

CYANOMETHYLENETRIBUTYLPHOSPHORANE Basic information

Product Name:	CYANOMETHYLENETRIBUTYLPHOSPHORANE
Synonyms:	Acetonitrile,2-(tributylphosphoranylidene)-;(Tributylphosphoranylidene)acetonitrile;(Tributylphosphoranylidene)acetonitrile solution;2-(tributylphosphoranylidene)acetonitrile;cyanomethylenetri-n-butylphosphorane90+%n;CynoMethylenetributyl phosphorane;2-(tributyl-l5-phosphanylidene)acetonitrile;CYANOMETHYLENETRIBUTYLPHOSPHORANE
CAS:	157141-27-0
MF:	C14H28NP
MW:	241.35
EINECS:
Product Categories:	pharmacetical;Tsunoda Reagent (Mitsunobu Reaction);Condensation & Active Esterification;Mitsunobu Reaction;Synthetic Organic Chemistry;s
Mol File:	157141-27-0.mol

CYANOMETHYLENETRIBUTYLPHOSPHORANE Chemical Properties

Boiling point	339.1±25.0 °C(Predicted)
density	0.921 g/mL at 25 °C
refractive index	n20/D1.500(lit.)
Fp	7 °C
storage temp.	2-8°C
form	clear liquid
color	Yellow to Amber to Dark purple
InChIKey	OZMLUMPWPFZWTP-UHFFFAOYSA-N

Safety Information

Hazard Codes	F,Xn
Risk Statements	10-23/24/25-67-65-48/20-38-11-63
Safety Statements	16-26-36/37/39-62-36/37
RIDADR	3275
WGK Germany	3
HS Code	2931499090

MSDS Information

CYANOMETHYLENETRIBUTYLPHOSPHORANE Usage And Synthesis

Uses	(Tributylphosphoranylidene)acetonitrile can be utilized as a reagent in the: Stereoselective synthesis of skytanthine and other O- and N-containing heterocycles by Mitsunobu intramolecular cycloalkylation. Wittig olefination of esters, lactones, N-Boc lactam, and cyclic imide to corresponding Wittig products.
General Description	(Tributylphosphoranylidene)acetonitrile is a stabilized trialkylphosphorane that can act as a substitute to the diethyl azodicarboxylate and triphenylphosphine (DEAD-TPP) system for Mitsunobu reaction between nucleophiles (HA) and alcohols (ROH) to form RA. It is highly useful when the pKa of the nucleophiles are higher than 11.

CYANOMETHYLENETRIBUTYLPHOSPHORANE Preparation Products And Raw materials

Raw materials

n-Butyllithium-->Benzene-->Hexane-->Nitromethane-->Chloroacetonitrile-->Tributylphosphine

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