(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
  • CAS No.:475473-26-8
Other grades of this product :
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Basic information
Product Name:(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
Synonyms:(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium;CORM-3;Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-;Carbon monoxide releasing molecule 3;Tricarbonylchloro(glycinato)ruthenium (II);Tricarbonylchloro(glycinato)ruthenium
CAS:475473-26-8
MF:C5H3ClNO5Ru
MW:293.6
EINECS:
Product Categories:Inhibitors
Mol File:475473-26-8.mol
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Chemical Properties
storage temp. -20°C
solubility H2O: soluble20mg/mL, clear
form powder
color light yellow to dark yellow
Safety Information
WGK Germany 3
MSDS Information
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Usage And Synthesis
UsesCORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H2O2-induced apoptosis using primary rabbit lens epithelial cells.
Biochem/physiol ActionsCORM-3 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase, has recently been found to be an important gaseous signaling mediator in mammalian cells CORM-3 has been shown to have anti-inflammatory and cardioprotective activity.
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Preparation Products And Raw materials

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