PHOSPHONOACETIC ACID
PHOSPHONOACETIC ACID
  • CAS No.:4408-78-0
Other grades of this product :
PHOSPHONOACETIC ACID Basic information
Product Name:PHOSPHONOACETIC ACID
Synonyms:PHOSPHONOETHANOIC ACID;PHOSPHONOACETIC ACID;AURORA KA-1453;Carboxymethanephosphonic acid;carboxymethanephosphonicacid;Fosfonet;Fosfonoacetic acid;Phosphonacetic acid
CAS:4408-78-0
MF:C2H5O5P
MW:140.03
EINECS:224-558-1
Product Categories:Phosphonic/Phosphinic AcidsEnzyme Inhibitors by Enzyme;Proline dipeptidase;Organic Building Blocks;P to;Phosphorus Compounds
Mol File:4408-78-0.mol
PHOSPHONOACETIC ACID Chemical Properties
Melting point 143-146 °C (lit.)
Boiling point 490.2±47.0 °C(Predicted)
density 1.858±0.06 g/cm3(Predicted)
refractive index 1.5180 (estimate)
storage temp. 2-8°C
solubility water: soluble100mg/mL, clear to very slightly hazy, colorless
pka1.74±0.10(Predicted)
Water Solubility Soluble in water.
Sensitive Hygroscopic
BRN 1764355
CAS DataBase Reference4408-78-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 26-36/37/39
RIDADR UN3261
WGK Germany 3
RTECS AJ3278000
HazardClass 8
PackingGroup III
HS Code 29319019
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
PHOSPHONOACETIC ACID Usage And Synthesis
Chemical PropertiesWhite powder
UsesAntiviral.
UsesPhosphonoacetic acid inhibits deoxyribo nucleic acid polymerase, especially in viruses. It is used as an antiviral agent. Further, it is used in the preparation of 1-(dimethylamino)-2,2-bis[(dimethylimmonio)-methyl]ethene diperchlorate by reacting with phosphorus oxychloride.
UsesPhosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner.
DefinitionChEBI: A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
PHOSPHONOACETIC ACID Preparation Products And Raw materials
Preparation ProductsFosinopril

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