Other grades of this product :
| CAY10602 Basic information |
| Product Name: | CAY10602 | | Synonyms: | CAY10602;1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine;SIRT1 Activator II - CAS 374922-43-7 - Calbiochem;CAY10602, >98%;1H-Pyrrolo[2,3-b]quinoxalin-2-amine, 1-(4-fluorophenyl)-3-(phenylsulfonyl)-;CAY10602 HCl | | CAS: | 374922-43-7 | | MF: | C22H15FN4O2S | | MW: | 418.44 | | EINECS: | | Product Categories: | | Mol File: | 374922-43-7.mol |
| CAY10602 Chemical Properties |
| Melting point | 270 °C | | storage temp. | +2C to +8C | | form | Off-white powder | | color | Light yellow to Amber to Dark green | | CAS DataBase Reference | 374922-43-7 |
| CAY10602 Usage And Synthesis |
| General Description | A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 μM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-α release in THP-1 cells by ~10-fold more potent than resveratrol (Cat. No. 554325). |
| CAY10602 Preparation Products And Raw materials |
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