Other grades of this product :
| D-alpha-Cyclohexylglycine Chemical Properties |
| Melting point | 256 °C | | alpha | -34.5 º (c=0.4 5N HCl) | | Boiling point | 292.8±23.0 °C(Predicted) | | density | 1.120±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO | | pka | 2.44±0.10(Predicted) | | form | Solid | | color | Off-White | | Water Solubility | Soluble | | BRN | 3196806 | | InChIKey | WAMWSIDTKSNDCU-SSDOTTSWSA-N | | CAS DataBase Reference | 14328-52-0(CAS DataBase Reference) |
| D-alpha-Cyclohexylglycine Usage And Synthesis |
| Description | D-alpha-Cyclohexylglycine is a kind of non-proteinogenic amino acid. It is widely presented in various natural products and pharmaceutical intermediates. It can be incorporated into the peptide inhibitors renders resistance from peptidases and proteinases and thereby imparts pharmacological stability to molecules. Some derivatives of Cyclohexylglycine has been recently been developed into inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes.
| | References | https://www.qmbio.com/?shopp_category=chg
Edmondson, Scott D., A. Mastracchio, and E. R. Parmee. "CYCLOHEXYLGLYCINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES." (2008).
Mastracchio, Anthony, et al. "Heterocycle-Fused Cyclohexylglycine Derivatives as Novel Dipeptidyl Peptidase-IV Inhibitors. " Cheminform 35.35(2004):203-206.
| | Chemical Properties | white powder | | Uses | D-Cyclohexylglycine (cas# 14328-52-0) is a compound useful in organic synthesis. |
| D-alpha-Cyclohexylglycine Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye