5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
  • CAS No.:28480-70-8
Other grades of this product :
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Basic information
Product Name:5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
Synonyms:5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE;5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE;4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE;1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE;2-ACETYL-4-CHLORO-5-METHYLPHENOL;5'-Chooro-2'-Hydroxy-4'-Methylacetophenone;JRH-01005, 1-(5-Chloro-2-hydroxy-4-methylphenyl)ethanone, 97%;4-Acetyl-2-chloro-5-hydroxytoluene 2-Acetyl-4-chloro-5-methylphenol
CAS:28480-70-8
MF:C9H9ClO2
MW:184.62
EINECS:
Product Categories:Ketones;Aromatic Acetophenones & Derivatives (substituted);C9;Carbonyl Compounds
Mol File:28480-70-8.mol
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Chemical Properties
Melting point 70-73 °C(lit.)
Boiling point 137 °C / 15mmHg
density 1.250±0.06 g/cm3(Predicted)
pka9.84±0.23(Predicted)
form powder to crystal
color White to Light yellow
CAS DataBase Reference28480-70-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
Hazard Note Irritant
MSDS Information
ProviderLanguage
SigmaAldrich English
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Usage And Synthesis
Uses5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:
  • chalcones, required for the synthesis of novel pyrazoline derivatives
  • 5′-chloro-2′-hydroxy-4′-methyl-3-(2′′-thienyl)acrylophenone
  • 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)
PreparationPreparation by reaction of acetic acid on 4-chloro-3- methylphenol with boron trifluoride at 70–100° (80–85%).
General Description5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone.
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Preparation Products And Raw materials
Preparation Products6-CHLORO-3-FORMYL-7-METHYLCHROMONE

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