4ALPHA-PHORBOL 12,13-DIDECANOATE

CAS No.：27536-56-7

Other grades of this product :

4ALPHA-PHORBOL 12,13-DIDECANOATE Basic information

Product Name:	4ALPHA-PHORBOL 12,13-DIDECANOATE
Synonyms:	4ALPHA-PDD;4ALPHA-PHORBOL 12-13-DICAPRINATE;4ALPHA-PHORBOL 12,13-DIDECANOATE;4a-Phorbol-12,13-didecanoate;4A-PHORBOL 12,13-DIDECANOATE WEAK PROTEI N KINASE C;4α-phorbol 12-13-dicaprinate;4A-PHORBOL 12,13-DIDECANOATE, 99+%;phorbol (4alpha-) 12,13-didecanoate
CAS:	27536-56-7
MF:	C40H64O8
MW:	672.93
EINECS:
Product Categories:	metabolite
Mol File:	27536-56-7.mol

4ALPHA-PHORBOL 12,13-DIDECANOATE Chemical Properties

storage temp.	-20°C
solubility	DMSO: soluble
form	solid
color	white
BRN	2514324

Safety Information

Hazard Codes	T+
Risk Statements	26/27/28-40-43
Safety Statements	36/37/39-45
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
F	8-10
HazardClass	6.1(b)
PackingGroup	III

MSDS Information

Provider	Language
SigmaAldrich	English

4ALPHA-PHORBOL 12,13-DIDECANOATE Usage And Synthesis

Uses	4α-Phorbol 12,13-didecanoate has been used as a transient receptor potential vanilloid 4 (TRPV4) agonist: to study its effects on Madin-Darby canine kidney (MDCK) cells to study its effects on Ca²⁺ influx in mice fallopian tubal cells to study its effects on hind paw swelling in mice
Biochem/physiol Actions	4α-Phorbol 12,13-didecanoate is a transient receptor potential vanilloid 4 (TRPV4) agonist. It promotes extracellular calcium influx into the cells.

4ALPHA-PHORBOL 12,13-DIDECANOATE Preparation Products And Raw materials

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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