2-Phenoxyaniline
2-Phenoxyaniline
  • CAS No.:2688-84-8
Other grades of this product :
2-Phenoxyaniline Basic information
Product Name:2-Phenoxyaniline
Synonyms:AURORA KA-7802;2-AMINOPHENYL PHENYL ETHER;2-AMINODIPHENYL ETHER;2-PHENOXYANILINE;AKOS B020146;O-PHENOXYANILINE;2-Ade;2-phenoxy-anilin
CAS:2688-84-8
MF:C12H11NO
MW:185.22
EINECS:220-254-8
Product Categories:
Mol File:2688-84-8.mol
2-Phenoxyaniline Chemical Properties
Melting point 47-49 °C(lit.)
Boiling point 170 °C18 mm Hg(lit.)
density 1.0936 (rough estimate)
refractive index 1.5300 (estimate)
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Slightly soluble in chloroform and methanol.
form Crystalline Powder or Flakes
pka3.78±0.10(Predicted)
color Brown to gray
BRN 777766
Stability:Hygroscopic
CAS DataBase Reference2688-84-8(CAS DataBase Reference)
NIST Chemistry Reference2-Aminodiphenyl ether(2688-84-8)
EPA Substance Registry Systemo-Phenoxyaniline (2688-84-8)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/37/38-22
Safety Statements 26-37/39-36/37/39-36
RIDADR 2811
WGK Germany 3
RTECS BY7940000
Hazard Note Irritant
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29222990
ToxicityLD50 ivn-mus: 212 mg/kg TXCYAC 8,347,77
MSDS Information
ProviderLanguage
2-Aminophenyl phenyl ether English
ACROS English
SigmaAldrich English
ALFA English
2-Phenoxyaniline Usage And Synthesis
Chemical PropertiesWhitetolightyellowcrystalpowde
Uses2-Phenoxyaniline serves as an antiinflammatory agent that inhibits preferentially COX-2 over COX-1. It is used in the preparation of sodium primary amide complex, 4-methyl-2-(2-phenoxyphenyl)azo-phenol and 2-acetoaminodiphenyl ether. Further, it is used to form complexes with beta-cyclodextrin.
Uses2-Phenoxyaniline may be used in the preparation of sodium primary amide complex, 2-PhOC6H4NHNa·NMe[(CH2)2NMe2]2. It was used in the preparation of 2-acetoaminodiphenyl ether. It may be used in the preparation of 4-methyl-2-(2-phenoxyphenyl)azo-phenol.
General Description2-Phenoxyaniline forms crystalline 2:1 (host-to-guest) inclusion complexes with β-cyclodextrin.
Safety ProfilePoison by intravenous route. When heated to decomposition it emits toxic vapors of NOx.
2-Phenoxyaniline Preparation Products And Raw materials
Preparation ProductsTriclosan-->4-Phenoxyaniline-->1-IODO-2-PHENOXY-BENZENE

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