5-NITRO-2-FUROYL CHLORIDE
5-NITRO-2-FUROYL CHLORIDE
  • CAS No.:25084-14-4
Other grades of this product :
5-NITRO-2-FUROYL CHLORIDE Basic information
Product Name:5-NITRO-2-FUROYL CHLORIDE
Synonyms:5-NITROFURAN-2-CARBONYL CHLORIDE;5-NITRO-2-FUROYL CHLORIDE;2-Furancarbonyl chloride, 5-nitro-;2-Furoyl chloride, 5-nitro-;5-nitrofuroyl chloride;Ai3-23633;Einecs 246-607-6;5-Nitro-2-furancarbonyl chloride
CAS:25084-14-4
MF:C5H2ClNO4
MW:175.53
EINECS:246-607-6
Product Categories:Building Blocks;C4 to C7;Chemical Synthesis;Furans;Heterocyclic Building Blocks
Mol File:25084-14-4.mol
5-NITRO-2-FUROYL CHLORIDE Chemical Properties
Melting point 34-41 °C
Boiling point 137-140°C 15mm
density 1.588±0.06 g/cm3(Predicted)
Fp 137-140°C/15mm
Sensitive Moisture Sensitive
BRN 139693
CAS DataBase Reference25084-14-4(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45
RIDADR 3261
WGK Germany 3
Hazard Note Corrosive
HazardClass 8
PackingGroup II
HS Code 2932190090
MSDS Information
ProviderLanguage
ALFA English
5-NITRO-2-FUROYL CHLORIDE Usage And Synthesis
Description5-Nitrofuroyl chloride is a furan chain bound to an acyl and a nitro group. Nitrofuran derivatives have been used as antibiotic and antimicrobial drugs but the acyl group bound to furan (furoyl chloride) is an intermediate for the synthesis of pharmaceuticals (e.g. antibiotics). 5-Nitrofuroyl chloride has been used as a reagent for the synthesis of some compounds with antibacterial properties and other chemicals.
Uses5-Nitrofuroyl chloride has been used in the synthesis of certain ureides of furanmonocarboxylic acid and in the synthesis of two salts of the mesoionic compound with an influence on the effectiveness of norfloxacin, tetracycline, and erythromycin. There is a study on the antibacterial effects of some 5-nirtofuroyl derivatives but not on 5-nitrofuroyl chloride. There are no reports on its commercial use.
Uses5-Nitro-2-furoyl Chloride is used as reactant in the synthesis of several therapeutic agents.
Environmental Fate5-Nitrofuroyl chloride is a colorless crystal with molecular weight of 175.53 g mol-1. It is stable under normal temperature and pressure on the basis of its melting point (38–14℃). There are no available data on its solubility in water. The bioaccumulation factor (BCF) for this compound is 4.29 at pH 7.4, which indicates low accumulation in aquatic organisms. The soil adsorption coefficient normalized to the content of organic carbon (Koc value) is 98.92 at pH 7.4, which indicates high mobility in soil.

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