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| 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Basic information |
| Product Name: | 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione | | Synonyms: | 7-Chloro-5-phenyl-1,5-dihydro-3H-1,5-benzodiazepine-2,4-dione;8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione;7-Chloro-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione;Desmethylclobazam;Norclobazam;1H-1,5-Benzodiazepine-2,4(3H,5H)-dione, 8-chloro-1-phenyl-;Clofazin;Demethylclobazam | | CAS: | 22316-55-8 | | MF: | C15H11ClN2O2 | | MW: | 286.71 | | EINECS: | 244-909-2 | | Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 22316-55-8.mol |
| 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Chemical Properties |
| Melting point | >239°C (dec.) | | Boiling point | 601.8±55.0 °C(Predicted) | | density | 1.363±0.06 g/cm3(Predicted) | | Fp | 2℃ | | storage temp. | Controlled Substance, -20°C Freezer | | pka | 7.57±0.20(Predicted) |
| 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Usage And Synthesis |
| Description | N-Desmethylclobazam (Item No. 18564) is an analytical reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam positively modulates GABAA receptors (EC50s range from 98 to 151 μM, depending on subunit configuration). This product is intended for research and forensic applications. | | Description | N-Desmethylclobazam (CRM) (Item No. 18888) is a certified reference material that is structurally categorized as a benzodiazepine. It is a major active metabolite of clobazam, produced primarily by the action of cytochrome P450 isoform 3A4. N-Desmethylclobazam (CRM) positively modulates GABAA receptors (EC50s range from 98 to 151 μM, depending on subunit configuration). This product is intended for research and forensic applications. | | Chemical Properties | Off-White Solid | | Uses | The major metabolite of Clobazam
Controlled substance (depressant). | | General Description | A Certified Solution Standard for use in LC or GC applications from forensic and forensic toxicology analysis to urine drug testing. N-Desmethylclobazam, found in urine, serum, and plasma, is the pharmacologically active, major metabolite of clobazam. |
| 8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione Preparation Products And Raw materials |
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