| 6-HYDROXYCHLORZOXAZONE Basic information |
| Product Name: | 6-HYDROXYCHLORZOXAZONE |
| Synonyms: | 5-chloro-6-hydroxy-2-benzoxazolinon;5-chloro-6-hydroxy-2-benzoxazolinone;CHLORZOXAZONE, 6-HYDROXY MAJOR METABOLIT E OF C;6-Hydroxychlorzoxazone solution ;6-Hydroxy Chlorzoxazone-15N-d2;5-Chloro-6-hydroxy-2(3H)-benzoxazolone, 5-Chloro-6-hydroxybenzoxazone;5-Chloro-6-hydroxybenzoxazol-2(3H)-one;5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one |
| CAS: | 1750-45-4 |
| MF: | C7H4ClNO3 |
| MW: | 185.56 |
| EINECS: | 621-147-2 |
| Product Categories: | Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals |
| Mol File: | 1750-45-4.mol |
| 6-HYDROXYCHLORZOXAZONE Chemical Properties |
| Melting point | 240-242°C |
| storage temp. | 2-8°C |
| solubility | methanol: soluble |
| form | Solid |
| color | white to pink |
| CAS DataBase Reference | 1750-45-4 |
| Safety Information |
| Hazard Codes | Xi,T,F |
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-45-36/37-16-7 |
| WGK Germany | 2 |
| RTECS | DM5260000 |
| HS Code | 29349990 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| 6-HYDROXYCHLORZOXAZONE Usage And Synthesis |
| Chemical Properties | Off-White Solid |
| Uses | 6-Hydroxychlorzoxazone has been used for HPLC-based metabolic assays of chlorzoxazone. |
| Uses | A major metabolite of chlorzoxazone. Formed by the actions of cytochrome P450IIE1 |
| Biochem/physiol Actions | 6-hydroxy Chlorzoxazone is a novel metabolite of chlorzoxazone. It is formed by the hydroxylation of chlorzoxazone by cytochrome P450 family 2 subfamily E member 1 (CYP2E1) enzyme. The determination of formation and clearance of 6-hydroxychlorzoxazone is used as a reliable marker of CYP2E1 metabolic activity. |
| 6-HYDROXYCHLORZOXAZONE Preparation Products And Raw materials |
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