5-METHOXYGRAMINE
5-METHOXYGRAMINE
  • CAS No.:16620-52-3
Other grades of this product :
5-METHOXYGRAMINE Basic information
Product Name:5-METHOXYGRAMINE
Synonyms:5-METHOXYGRAMINE 99%;5-Methoxygramine, N,N-Dimethyl-(5-methoxy-1H-indol-3-yl)methylamine;methoxygramine;5-Methoxygramine or 5-Methoxy-3-(Dimethylaminomethyl)-indole;(5-methoxy-1H-indol-3-yl)methyl-dimethylammonium;3-ETHYL-1H-PYRAZOL-5-AMINE HCL;5-Methoxygramine,99%;NSC 88885
CAS:16620-52-3
MF:C12H16N2O
MW:204.27
EINECS:240-669-8
Product Categories:Building Blocks;C12;Indoline & Oxindole;Chemical Synthesis;Heterocyclic Building Blocks;Indoles;Indoles and derivatives;Heterocyclic Compounds
Mol File:16620-52-3.mol
5-METHOXYGRAMINE Chemical Properties
Melting point 123-126 °C (lit.)
Boiling point 342.77°C (rough estimate)
density 1.0565 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Refrigerator (+4°C)
pka16.70±0.30(Predicted)
BRN 170533
CAS DataBase Reference16620-52-3(CAS DataBase Reference)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-22
Safety Statements 22-24/25
WGK Germany 3
RTECS NL7700000
10
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
5-METHOXYGRAMINE Usage And Synthesis
Chemical Propertieswhite to almost white crystalline powder
Uses• ;Reactant for preparation of dopamine D2 receptor antagonists1• ;Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction2• ;Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands3• ;Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents4• ;Reactant for preparation of in
Uses
  • Reactant for preparation of dopamine D2 receptor antagonists
  • Reactant for asymmetric preparation of ethenyl(tetrahydro)carbazoledicarboxylates via gold(I)-catalyzed intramolecular Friedel-Crafts allylic alkylation reaction
  • Reactant for preparation of N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ols as dopamine D2-like receptor ligands
  • Reactant for preparation of substituted N-trimethoxybenzoyl indoles, indolines, and a tetrahydroquinoline via N-aroylation with trimethoxybenzoyl chloride or anhydride as antitubulin agents
  • Reactant for preparation of indolylmethanesulfonamide and its methoxy derivatives
5-METHOXYGRAMINE Preparation Products And Raw materials
Raw materialsSodium hydroxide-->Hydrochloric acid-->Diethyl ether-->Acetic acid-->Formaldehyde-->Dimethylamine-->5-Methoxyindole

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