4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
  • CAS No.:159191-56-7
Other grades of this product :
4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID Basic information
Product Name:4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
Synonyms:oxy)phenyL;4-(T-BUTYL DIMETHYLSILOXY) PHENYL BORONIC ACID;4-(TERT-BUTYL DIMETHYLSILOXY)PHENYL BORONIC ACID;4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID;4-(TERT-BUTYLDIMETHYLSILYOXY)PHENYLBORONIC ACID;AKOS BRN-0412;4-(TERT-BUTYLDIMETHYLSILYOXY)PHENYLBORON;4-(tert-Butyldimethylsilyloxy)benzeneboronic acid
CAS:159191-56-7
MF:C12H21BO3Si
MW:252.19
EINECS:
Product Categories:blocks;BoronicAcids;Aryl;Organoborons;Boronic acid;Boronic Acids;Boronic Acids;Boronic Acids and Derivatives;Aryl Boronic Acids;Boronic Acids and Derivatives;Chemical Synthesis;Monosubstituted Aryl Boronic Acids;Organometallic Reagents
Mol File:159191-56-7.mol
4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID Chemical Properties
Melting point 194-198 °C (lit.)
Boiling point 321.4±44.0 °C(Predicted)
density 1.01±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form powder to crystal
pka8.68±0.16(Predicted)
color White to Almost white
Safety Information
Hazard Codes Xi
WGK Germany 3
HS Code 2931900090
MSDS Information
ProviderLanguage
SigmaAldrich English
4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID Usage And Synthesis
UsesReactant involved in:• ;Asymmetric addition reactions with β-substituted cyclic enones1• ;Hydroarylation and heterocyclization with phenylpropiolates2• ;Double Suzuki-Miyaura coupling reactions3Starting material for the synthesis of red electroluminescent polyfluorenes4Reactant involved in the synthesis of biologically active molecules including:• ;Phenylpyridone derivatives as MCH1R antagonists5• ;Atromentin and its O-alkylated derivatives3• ;Gelatinases and MT1-MMP inhibitors6
UsesReactant involved in:
  • Asymmetric addition reactions with β-substituted cyclic enones
  • Hydroarylation and heterocyclization with phenylpropiolates
  • Double Suzuki-Miyaura coupling reactions
Starting material for the synthesis of red electroluminescent polyfluorenesReactant involved in the synthesis of biologically active molecules including:
  • Phenylpyridone derivatives as MCH1R antagonists
  • Atromentin and its O-alkylated derivatives
  • Gelatinases and MT1-MMP inhibitors
4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID Preparation Products And Raw materials
Raw materials(4-BROMOPHENOXY)-TERT-BUTYLDIMETHYLSILANE-->Triisopropyl borate-->tert-Butyldimethylsilyl chloride-->4-Hydroxyphenylboronic acid-->4-Bromophenol-->Trimethyl borate
Preparation Products4-Hydroxy-4'-fluorobiphenyl

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