5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
  • CAS No.:1434-54-4
Other grades of this product :
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Basic information
Product Name:5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
Synonyms:5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE;5-pregnen-3B-ol-20-one-16A-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;(3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile;pregnenolone-16α-carbonitrile;16α-Cyano-3β-hydroxypregn-5-en-20-one;U-14975;16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
CAS:1434-54-4
MF:C22H31NO2
MW:341.49
EINECS:
Product Categories:
Mol File:1434-54-4.mol
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Chemical Properties
Melting point 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2))
Boiling point 508.5±50.0 °C(Predicted)
density 1.13±0.1 g/cm3(Predicted)
Fp 93 °C
storage temp. 2-8°C
form White to off-white solid.
pka14.95±0.70(Predicted)
EPA Substance Registry SystemPregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)
Safety Information
WGK Germany 3
RTECS TU4536500
MSDS Information
ProviderLanguage
SigmaAldrich English
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Usage And Synthesis
UsesPregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Biochem/physiol ActionsPregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Preparation Products And Raw materials

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