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| STRYCHNINE HYDROCHLORIDE Basic information |
| Product Name: | STRYCHNINE HYDROCHLORIDE | | Synonyms: | (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one:hydrochloride;Strychnidin-10-one hydrochloride (1:1);(4aR,4a1R,5aS,8aR,8a1S,15aS)-4a1,5,5a,7,8,8a1,15,15a-Octahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14(4aH)-one hydrochloride;Strychnine Hydrochloride Hydrate;STRYCHNINE HCL;STRYCHNINE HYDROCHLORIDE;Strychnidin-10-one, monohydrochloride (9ci);Strychnidin-10-onehydrochloride | | CAS: | 1421-86-9 | | MF: | C21H23ClN2O2 | | MW: | 370.87 | | EINECS: | 215-826-9 | | Product Categories: | GABA and Glycine Receptor ModulatorsNeurotransmission;Glycinergics;chiral;Ion Channels;Ligand-Gated Ion Channels;Neurotransmitters;Alkaloids;Biochemistry;for Resolution of Acids;Indole Alkaloids;Optical Resolution;Synthetic Organic Chemistry | | Mol File: | 1421-86-9.mol |
| STRYCHNINE HYDROCHLORIDE Chemical Properties |
| STRYCHNINE HYDROCHLORIDE Usage And Synthesis |
| Uses | Strychnine Hydrochloride acts as an antagonist for cholinesterases and beta amyloid aggregation. | | Uses | Strychnine hydrochloride has been used as a glycine receptor antagonist in the retina for biophysiological functions. It has also been used to block glutamatergic, GABAergic and glycinergic receptors and gap junctions. | | Definition | ChEBI: A hydrochloride obtained by combining strychnine with one molar equivalent of hydrogen chloride. | | Biological Activity | Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α 7 receptors and non-competitive antagonism at α 4 β 2 receptors. | | Biochem/physiol Actions | Strychnine is a potent convulsant, which is extracted from Strychnos nux vomica seeds. At high doses, the compound causes convulsions and ultimately death due to respiratory paralysis. Strychnine acts as a respiratory, circulatory and digestive stimulant. |
| STRYCHNINE HYDROCHLORIDE Preparation Products And Raw materials |
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