H-GLY-PRO-ARG-PRO-NH2
H-GLY-PRO-ARG-PRO-NH2
  • CAS No.:126047-75-4
Other grades of this product :
H-GLY-PRO-ARG-PRO-NH2 Basic information
Product Name:H-GLY-PRO-ARG-PRO-NH2
Synonyms:H-GLY-PRO-ARG-PRO-NH2;GLY-PRO-ARG-PRO AMIDE PEPTIDE;H2N-GPRP-AMIDE;GPRP-NH2;gly-pro-arg-pro amide;gly-pro-arg-pro amide acetate;H-Gly-Pro-Arg-Pro-NH acetate salt;H-Gly-Pro-Arg-Pro-NH2/GPRP-NH2
CAS:126047-75-4
MF:C18H32N8O4
MW:424.5
EINECS:
Product Categories:Clotting FactorsPeptides for Cell Biology;Clotting InhibitorsProteins and Derivatives;Blood;Coagulation Proteins and Reagents;Extracellular Matrix Peptides (ECM);Immune Cell Signaling and Blood;Plasma&Blood Proteins
Mol File:126047-75-4.mol
H-GLY-PRO-ARG-PRO-NH2 Chemical Properties
storage temp. -20°C
Safety Information
WGK Germany 3
MSDS Information
H-GLY-PRO-ARG-PRO-NH2 Usage And Synthesis
UsesGly-Pro-Arg-Pro amide has been used-
  • as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombin
  • for blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from mice
  • during preparation of human soluble fibrin, to block the polymerization of soluble fibrin
General DescriptionGly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein.
Biochem/physiol ActionsGly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).
H-GLY-PRO-ARG-PRO-NH2 Preparation Products And Raw materials

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