Sulfobromophthalein sodium
Sulfobromophthalein sodium
  • CAS No.:123359-42-2
Other grades of this product :
Sulfobromophthalein sodium Basic information
Product Name:Sulfobromophthalein sodium
Synonyms:BROMOSULFOPHTHALEIN;BROMOSULFOPHTHALEIN SODIUM SALT;BROMO SULPHALEIN;BROMOSULPHALEIN DISODIUM SALT;3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3h)-isobenzofuranylidene)bis(6-hydroxy-benzenesulfonic acid) disodium salt;bromsulfalein sodium;SULFORBROMOPHTHALEINSODIUMHYDRATE;PHENOLTETRABROMOPHTHALEIN-3',3''-DISULFONIC ACID DISODIUM SALT
CAS:123359-42-2
MF:C20H13Br4NaO11S2
MW:836.04
EINECS:626-376-1
Product Categories:
Mol File:123359-42-2.mol
Sulfobromophthalein sodium Chemical Properties
Melting point >235°C (dec.)
storage temp. room temp
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Crystalline Powder
color White
CAS DataBase Reference123359-42-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 42/43-R42/43
Safety Statements 22-36/37-45-S45-S36/37-S22
WGK Germany 3
RTECS SM8395000
HS Code 29329900
MSDS Information
ProviderLanguage
SigmaAldrich English
Sulfobromophthalein sodium Usage And Synthesis
DescriptionA blue dye used in the assessment of hepatobiliary dysfunction. The concentration in plasma is monitored since dye removal from the blood is delayed in hepatic dysfunction. Experimentally the appearance of sulfobromphthalein in the bile can also be measured.
Chemical PropertiesWhite, crystalline powder; odorless; bit- ter taste. Hygroscopic; soluble in water; insoluble in alcohol and acetone.
UsesMedicine (diagnostic aid).
UsesSulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto-β-boswellic acid (KBA) and 3-acetyl-11-keto-β-boswellic acid (AKBA) with organic anion transporter OATP1B3.
Biochem/physiol ActionsSulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20.
Sulfobromophthalein sodium Preparation Products And Raw materials

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