2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
  • CAS No.:123021-85-2
Other grades of this product :
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Basic information
Product Name:2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
Synonyms:2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid;2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid;GPR35 Agonist, Compound 10;GPR35 Agonist, Compound 10 >=98% (HPLC);2-{4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]p henoxy}acetic acid
CAS:123021-85-2
MF:C12H9NO5S
MW:279.27
EINECS:
Product Categories:
Mol File:123021-85-2.mol
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Chemical Properties
storage temp. 2-8°C
solubility DMSO: ≥5mg/mL at ~60°C
form powder
color white to tan
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
WGK Germany 3
MSDS Information
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Usage And Synthesis
UsesGPR35 Agonist, Compound 10, may be used in GPR35-mediated cell signaling studies.
Biochem/physiol ActionsGPR35 agonist Compound 10 is a GPR35 agonist the binds with higher affinity than other known agonists, such as kynurenic acid and zaprinast. Compound 10 was more potent than zaniprast (pEC50 = 5.3 vs 4.18) for recombinantly expressed human GPR35, and unlike zaprinast, is equipotent for human and rat GPR35
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Preparation Products And Raw materials

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