1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE&
1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE&
  • CAS No.:122296-00-8
Other grades of this product :
1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE& Basic information
Product Name:1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE&
Synonyms:1-((Trimethylsilyl)methyl)-1H-benzo[d][1,2,3]triazole;1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE 99%;benzotriazol-1-ylmethyl(trimethyl)silane;1H-Benzotriazole, 1-[(trimethylsilyl)methyl]-;1-[(Trimethylsilyl)Methyl]-1H-1,2,3-Benzotriazole
CAS:122296-00-8
MF:C10H15N3Si
MW:205.33
EINECS:
Product Categories:C-C Bond Formation;Others;Synthetic Reagents
Mol File:122296-00-8.mol
1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE& Chemical Properties
Melting point 56-60 °C(lit.)
solubility Well soluble in most organic solvents.
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE& Usage And Synthesis
Physical propertiesmp 55–56 °C.
Uses1-[(Trimethylsilyl)methyl]- 1H-benzotriazole is a reagent in the preparation of ketones, carboxylic acids,One-carbon Homologation of Carboxylic Acids,Synthesis of Fused Heterocycles and fused heterocycles.
UsesNew Benzotriazole ReagentsReactant for:
  • Alkylation reactions
  • Preparation of inhibitor of p53-MDM2 complex formation
  • Used as a one-carbon synthon for one-carbon homologation of carboxylic acids
Preparation1-[(trimethylsilyl)methyl]-1H-benzotriazole is readily prepared in a reaction of sodium benzotriazolide with chloromethyltrimethylsilane.
1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE& Preparation Products And Raw materials

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