TRIISOBUTYLAMINE

CAS No.：1116-40-1

Other grades of this product :

TRIISOBUTYLAMINE Basic information

Product Name:	TRIISOBUTYLAMINE
Synonyms:	1-Propanamine, 2-methyl-N,N-bis(2-methylpropyl)-;2-methyl-n,n-bis(2-methylpropyl)-1-propanamin;2-methyl-n,n-bis(2-methylpropyl)-1-propanamine;N,N-Diisobutyl-2-methyl-1-propanamine;tributylamine(non-specificname);tris(2-methylpropyl)amine;TRIISOBUTYLAMINE;2-methyl-N,N-bis(2-methylpropyl)propan-1-amine
CAS:	1116-40-1
MF:	C12H27N
MW:	185.35
EINECS:	214-236-9
Product Categories:	Amines;C11 to C38;Nitrogen Compounds
Mol File:	1116-40-1.mol

TRIISOBUTYLAMINE Chemical Properties

Melting point	-21.8°C
Boiling point	192-193 °C/770 mmHg (lit.)
density	0.766 g/mL at 25 °C (lit.)
refractive index	n20/D 1.423(lit.)
Fp	135 °F
pka	pK1:10.42(+1) (25°C)
form	clear liquid
color	Colorless to Almost colorless
BRN	1698950
EPA Substance Registry System	Triisobutylamine (1116-40-1)

Safety Information

Hazard Codes	Xi,N,T
Risk Statements	36/37/38-51/53-41-38-23/24-22
Safety Statements	26-36-61-45-36/37
RIDADR	UN 1993 3/PG 3
WGK Germany	3
F	9-34
HazardClass	8
PackingGroup	II

MSDS Information

Provider	Language
SigmaAldrich	English

TRIISOBUTYLAMINE Usage And Synthesis

Chemical Properties	Triisobutylamine is flammable.
Uses	Triisobutylamine is suitable to develop second generation ionic liquid matrices for MALDI-MS of peptides, proteins and carbohydrates. It may be used in the separation of cis-fatty acid salts and and trans-fatty acid (elaidic acid) salts using a new organic solvent nanofiltration membrane based on polydicyclopentadiene. It may be used as base in the synthesis of acroyl ammonium derivatives.
Production Methods	Triisobutylamine is manufactured from isobutanol and ammonia under heat and pressure.
General Description	Clear pale yellow liquid.
Air & Water Reactions	Insoluble in water.
Reactivity Profile	TRIISOBUTYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard	ACUTE/CHRONIC HAZARDS: Toxic.
Fire Hazard	TRIISOBUTYLAMINE is combustible.

TRIISOBUTYLAMINE Preparation Products And Raw materials

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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