Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
  • CAS No.:105228-46-4
Other grades of this product :
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Basic information
Product Name:Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
Synonyms:BENZYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE;(2S,3R)-benzyl 6-oxo-2,3- diphenylmorpholine-4-carboxylate;4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, phenylmethyl ester, (2S,3R)-;3-diphenyl-;4-Morpholinecarboxylicacid;6-oxo-2;(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylMorpholine;(5S,6R)-(+)-4-Benzyloxycarbonyl-5,6-diphenyl-2-Morpholinone
CAS:105228-46-4
MF:C24H21NO4
MW:387.43
EINECS:
Product Categories:Chiral Building Blocks;Heterocyclic Building Blocks;Morpholines
Mol File:105228-46-4.mol
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Chemical Properties
Melting point 205-207 °C(lit.)
alpha 66 º (c=5.5 in methylene chloride)
Boiling point 583.5±50.0 °C(Predicted)
density 1.242±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka-3.33±0.60(Predicted)
optical activity[α]25/D +66°, c = 5.5 in methylene chloride
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Usage And Synthesis
Uses(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylmorpholine can be used as a starting material for the synthesis of:
  • α-Amino-β-silyloxy-ester, a key intermediate for the preparation of antimalarial drug quinine and its analogs.
  • R, R-Formylglycine dimethylacetal, a key intermediate for the preparation of tuberculostatic compound capreomycin IB.
  • 2R,5R,6S-2-(Methoxycarbonylmethyl)-5,6-diphenylmorpholine hydrochloride, a key intermediate for the preparation of an antibiotic (+)-negamycin.
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Preparation Products And Raw materials

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