1,2-Dibromoethane-1-sulfonyl fluoride
1,2-Dibromoethane-1-sulfonyl fluoride
  • CAS No.:103020-97-9
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1,2-Dibromoethane-1-sulfonyl fluoride Basic information
Product Name:1,2-Dibromoethane-1-sulfonyl fluoride
Synonyms:1,2-Dibromoethane-1-sulfonyl fluoride;Ethanesulfonyl fluoride, 1,2-dibromo-;1,2-dibromo-Ethanesulfonyl fluoride
CAS:103020-97-9
MF:C2H3Br2FO2S
MW:269.92
EINECS:
Product Categories:
Mol File:103020-97-9.mol
1,2-Dibromoethane-1-sulfonyl fluoride Chemical Properties
Boiling point 276.7±30.0 °C(Predicted)
density 2.351±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
1,2-Dibromoethane-1-sulfonyl fluoride Usage And Synthesis
Uses1,2-Dibromoethane-1-sulfonyl fluoride (DESF) is a bench-stable precursor to 1-bromoethene-1-sulfonyl fluoride (BESF), a new and robust connective hub for the Sulfur (VI) fluoride exchange (SuFEx) click reaction. BESF offers similar routes as ethenesulfonyl fluoride (ESF, cat# 746959) but with additional reactivity due to the embedded bromo group.Treatment of DESF with triethylamine generates BESF in situ, which has been used to synthesize diverse and unprecented sulfonyl fluorides in good-to-excellent yields. As the resulting molecules possess sulfonyl fluoride handles, further SuFEx reactions are also possible. DESF adds another useful tool for conjugation strategies in chemical biology and organic and polymer synthesis.
1,2-Dibromoethane-1-sulfonyl fluoride Preparation Products And Raw materials

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