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| 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT Basic information |
| Product Name: | 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT | | Synonyms: | 4-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4-oxobutanoic acid;CHOLESTERYL HYDROGEN SUCCINATE TRIS SALT;CHOLESTERYL HEMISUCCINATE TRIS SALT;3β-hydroxy-5-cholestene 3-hemisuccinate;CHEMS;5-CHOLESTEN-3BETA-OL 3-HEMISUCCINATE TRIS SALT;3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT;CHOLESTERYL HEMISUCCINATE F & D VERSION& | | CAS: | 102601-49-0 | | MF: | C35H61NO7 | | MW: | 607.87 | | EINECS: | | Product Categories: | | Mol File: | 102601-49-0.mol |
| 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT Chemical Properties |
| 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT Usage And Synthesis |
| Uses | Cholesteryl hemisuccinate tris salt has been used:- to prepare solubilization buffer for glucan synthase assay
- to prepare immunoprecipitation buffer for immobilization of opioid receptors on paramagnetic beads.
- as a membrane stabilizer for liposomes and protein synaptogyrin-1
- as a component of a folate-modified self-microemulsifying drug delivery system.
- with N-dodecyl β-D-maltoside (DDM) to solubilize erythrocyte ghosts and chemokine receptor CCR1
- for protein solubilization
| | Biochem/physiol Actions | Cholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer drugs, oligonucleotides and antibiotics. Cholesteryl succinate also reportedly exhibits antiproliferative activity and may be clinically useful as antitumor agent. |
| 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT Preparation Products And Raw materials |
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