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| Abacavir Carboxylate Basic information |
| Product Name: | Abacavir Carboxylate | | Synonyms: | Abacavir Carboxylate;(1S,4R)-4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid;2269W;(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-ene-1-carboxylic acid;(1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enecarboxylic acid;2-Cyclopentene-1-carboxylic acid, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-;Abacavir Impurity 14 | | CAS: | 384380-52-3 | | MF: | C14H16N6O2 | | MW: | 300.32 | | EINECS: | | Product Categories: | Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals;Bases & Related Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Nucleotides;Pharmaceuticals | | Mol File: | 384380-52-3.mol |
| Abacavir Carboxylate Chemical Properties |
| Melting point | 208-210°C (dec.) | | storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | | form | Solid | | color | Off-White to Pale Beige | | Stability: | Hygroscopic |
| Abacavir Carboxylate Usage And Synthesis |
| Description | Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir . It is formed from abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues. | | Chemical Properties | Off-White Solid | | Uses | A major metabolite of Abacavir | | Uses | Abacavir Carboxylate (Abacavir - In House Impurity) is a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3). |
| Abacavir Carboxylate Preparation Products And Raw materials |
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