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| RAC ALBUTEROL-D9 Basic information |
| RAC ALBUTEROL-D9 Chemical Properties |
| Melting point | 142-146°C | | storage temp. | -20°C Freezer | | solubility | Methanol (Slightly), Water (Slightly) | | form | neat | | color | White to Yellow |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| RAC ALBUTEROL-D9 Usage And Synthesis |
| Description | Salbutamol-d9 is intended for use as an internal standard for the quantification of salbutamol (Item Nos. 21003 | 23991) by GC- or LC-MS. Salbutamol is an agonist of the β2-adrenergic receptor (β2-AR; Kd = 759 nM in a radioligand binding assay using CHO cells expressing the human receptor). It is selective for β2-ARs over β1- and β3-ARs (Kds = 46.8 and 21.9 μM, respectively). Salbutamol (25-50 μg/kg, i.v.) reduces acetylcholine-induced bronchospasm in anesthetized guinea pigs. It also reduces response of bronchial muscle to efferent vagal stimulation in anesthetized cats and dogs when administered at doses ranging from 1 to 2.5 and 10 to 20 μg/kg, respectively. Nebulized salbutamol reduces transpulmonary pressure in recurrent airway obstruction-affected horses (EC50 = 39.7 μg). Formulations containing salbutamol have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). | | Chemical Properties | Off-White to Pale Yellow Solid | | Uses | A labelled β2-adrenoceptor agonist. Bronchodilator; tocolytic. | | Uses | RAC ALBUTEROL-D9 is a labelled β2-adrenoceptor agonist,it is intended for use as an internal standard for the quantification of Albuterol by GC- or LC-mass spectrometry.
| | Uses | A labeled ?-adrenoceptor agonist |
| RAC ALBUTEROL-D9 Preparation Products And Raw materials |
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