H-77

Overview

H-77 is a selective Renin inhibitor with an IC 50 of 1.2 μM. H-77 causes dose-dependent decreases in plasma angiotensin I, plasma angiotensin II, and mean arterial pressure in sodium-depleted conscious beagle dogs. H-77 does not alter blood pressure or plasma angiotensin II levels in conscious chronically cannulated rats. H-77 can be used in studies related to the physiological and pathological states of the renin-angiotensin system.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Renin | Products > Signaling Pathways > Angiotensin Receptor

Product Information

• Catalog No.: HY-P2647
• CAS No.: 82131-82-6
• Molecular Formula: C52H74N12O9
• Molecular Weight: 1011.24
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source